NCT06715709
How Many Dexamethasone Doses Should Be Given Perioperatively?
Enrolling by Invitation
PHASE4Ages 18+InterventionalPreventionMayo ClinicInvestigator-initiated
~339 participants
Updated 2026-02-06 on ClinicalTrials.gov
What's tested:Dexamethasone IVDexamethasone IV+OralDexamethasone IV+Oral 2 Day
At a glance
Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Opioid consumption
Measured over 72 hours
Conditions
Where it's being run
1 sites across 1 statesMinnesota1
Study leadership
- Charles Hannon · PRINCIPAL_INVESTIGATOR · Mayo Clinic
Who to contact
This trial hasn't published a contact. View it on ClinicalTrials.gov
Do you actually qualify for this trial?
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Eligibility criteria
Inclusion
Age \> 18 years
Primary total knee arthroplasty
Exclusion
Age \< 18 year
Revision or unicompartmental knee arthroplasty
Corticosteroid use within 3 months prior to TKA
Inflammatory arthritis
Current systemic fungal infection
Renal or liver failure
Prior adverse reaction to corticosteroid
Primary TKA requiring hardware removal
What this trial measures
- Opioid consumption72 hours
Cumulative opioid consumption within 72 hours after Total Knee Arthroplasty, measured in oral morphine milligram equivalents.