GET ActivE Study for At-risk Youth

This study, called GET ActivE, is looking at whether an app called Vira, combined with support from a health coach, can help teenagers aged 12-18 who are dealing with depression and anhedonia (a reduced ability to feel pleasure). You would be randomly assigned to one of two groups: either using the Vira app with health coaching (GET ActivE) or using an app that tracks activity without coaching. The researchers want to see if the GET ActivE approach is practical, acceptable, and helps improve feelings of pleasure and reduce depression and suicidal thoughts. The study aims to enroll 75 participants, but its current status is unclear.

Study design
This is an interventional study with 75 participants, where you would be randomly assigned to one of two groups.
What's involved
You would need to download an app on your smartphone and engage with a health coach if assigned to the GET ActivE group. The study will last up to 3 months.
Compensation
Not stated in the trial record.
Follow-up
You would be followed for up to 3 months after the intervention.

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NCT06829953

Get ActivE Study for At-risk Youth

Recruiting
NAAges 12–18InterventionalTreatment
University of Pittsburgh
~75 participants
Updated 2026-06-04 on ClinicalTrials.gov
What's tested:GET ActivETreatment As Usual

At a glance

Recruiting sites
2 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
GET ActivE Feasibility
Measured over 3 months
+3 more outcomes measured
Anhedonia
Depression and Suicide Ideation
2 sites across 1 states
Pennsylvania2
  • Jamie Zelazny, PhD, MPH, RN · PRINCIPAL_INVESTIGATOR · University of Pittsburgh

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Adolescents age 12-18
Current moderate to severe depression (PHQ-9-M \> 11)
Current clinically significant anhedonia, operationalized as PHQ-9-M anhedonia item score \> 1
English language fluency and literacy level sufficient to engage in study protocol
Willing to download the app on their smart phones

Exclusion

Evidence of mania, psychosis, or developmental disability precluding comprehension of study procedures per electronic health record review and phone screen.
  • GET ActivE Feasibility3 months

    The study will observe high GET ActivE intervention feasibility (50% of eligible youth approached will enroll; completion \>50%; attrition \<20%)

  • Response to Health coach contacts3 months

    Participants will respond to health coach contacts \>80%

  • GET ActivE AcceptabilityPost intervention follow up; up to 3 months

    Acceptability of the GET ActivE intervention will be assessed through the 4 item Acceptability of Intervention Measure (AIM). Individual item scores are summed. Scale values range from 1 to 5. No items are reverse scored. Higher scores indicate greater acceptability. The items include questions to determine if intervention is appealing to, liked by, welcomed by, and approved by study population.

  • GET ActivE AppropriatenessPost intervention follow up; up to 3 months

    Intervention appropriateness of the GET ActivE intervention will be assessed through 4 item Intervention Appropriateness Measure (IAM). Individual item scores are summed. Scale values range from 1 to 5. No items are reverse scored. Higher scores indicate greater appropriateness. The items include questions to determine if intervention is a good match, fitting, suitable, or seems applicable to the study population.