Ketamine for Pain, Opioid Use, and Mental Health in Orthopedic Trauma Patients
This study is looking at whether a single dose of ketamine, given during surgery, can help adults recovering from serious orthopedic trauma. The goal is to see if ketamine reduces pain after surgery, lowers the amount of opioid pain medication needed, and improves mental health issues like depression and post-traumatic stress disorder (PTSD). You might be able to join if you are an adult aged 18-65, are having surgery for a musculoskeletal (bone and muscle) trauma, and meet other specific health criteria. The study will compare patients who receive ketamine to those who receive standard general anesthesia. Researchers will measure your pain levels and mental health over several months to see if ketamine makes a difference. The current status of this study is unclear, and it plans to enroll 90 participants.
- Study design
- This is an interventional study that plans to enroll 90 participants. It is a single-blind randomized controlled trial, meaning some participants will receive ketamine and others will receive standard anesthesia, but you won't know which one you're getting.
- What's involved
- Not specified in the trial record.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your pain intensity will be measured at several points, including 1-7 days, 2-3 weeks, 6 weeks, 3 months, and 6 months after your surgery.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Ketamine for Pain, Opioid Use, and Mental Health in Orthopedic Trauma Patients
At a glance
Conditions
Where it's being run
2 sites across 1 statesStudy leadership
- Max Evan Davis, MD · PRINCIPAL_INVESTIGATOR · Texas Tech University Health Sciences Center Department of Orthopaedic Surgery,
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Pain Intensity (VAS)1-7 days, 2-3 weeks (±1 week), 6 weeks (±2 weeks), 3 months (±3 weeks), and 6 months (±5 weeks) postoperatively.
Pain intensity will be assessed using the Visual Analog Scale (VAS), a validated 0-100 continuous scale (or 0-10 categorical equivalent). Higher scores indicate greater pain. This outcome evaluates whether intraoperative ketamine reduces postoperative pain compared to standard anesthesia.