Optimizing Care for Cancer Survivors With Depression: Project 3

This study is looking at different ways to treat depression in cancer survivors. A cancer survivor is anyone who has been diagnosed with cancer and is still living. You might be able to join if you are 18 or older, have elevated depressive symptoms (a PHQ-9 score of 8 or higher), are not currently getting depression treatment, and can use telehealth and an app called Moodivate. The study will randomly assign you to either use the Moodivate app, which helps track mood and activities, or have telehealth sessions with a mental health provider. Some people who start with Moodivate might also get telehealth sessions later. The main goal is to see if these digitally-enhanced approaches are practical for treating depression in cancer survivors. The study is currently unclear on its status and plans to enroll 45 participants.

Study design
This is an interventional study where participants are randomly assigned to one of two treatment groups. Approximately 45 participants will be enrolled.
What's involved
Participants will complete questionnaire measures at weeks 12, 16, 20, and 24 after being assigned to a group. If assigned to telehealth, you will have 8 sessions over 10 weeks.
Compensation
Not stated in the trial record.
Follow-up
The feasibility of the treatment approach will be measured at 24 weeks.

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NCT06930729

Optimizing Care for Cancer Survivors With Depression: Project 3

Recruiting
NAAges 18+InterventionalTreatment
Medical University of South Carolina
~45 participants
Updated 2026-07-14 on ClinicalTrials.gov
What's tested:Behavioral Activation Therapy AppTelehealth Delivered Behavioral Activation

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Feasibility of a digitally-enhanced stepped care approach to depression treatment among cancer survivors.
Measured over 24 weeks
Cancer
Depression
1 sites across 1 states
South Carolina1
  • Jennifer Dahne, MD · PRINCIPAL_INVESTIGATOR · Medical University of South Carolina

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

age 18+
cancer survivor
current elevated depressive symptoms defined per ASCO as a PHQ-9 score ≥ 8
not currently receiving psychosocial depression treatment
have the ability to complete treatment via telehealth and use Moodivate
have a valid e-mail address or text message access (for assessments)
English fluency
  • Feasibility of a digitally-enhanced stepped care approach to depression treatment among cancer survivors.24 weeks

    Feasibility will be defined as either use of the digital mental health intervention (DMHI) at least once per week for \>4 weeks (for DMHI engagers) or attendance at \>4 therapy sessions (for DMHI non-engagers). Digitally-enhanced stepped care will be considered feasible if \>80% of participants meet feasibility benchmarks.