Understanding Mental Health Treatments at Greenbrook

This study is looking back at information from Greenbrook's patient records to understand how well different mental health treatments work. It's examining patients who received NeuroStar TMS (a non-invasive brain stimulation device) or Esketamine (a nasal spray for depression). The study aims to see how much people's clinical outcome scores improved from before treatment to 8 weeks after treatment. This study is open to males and females aged 5 to 100 years old, as long as their treatment date was in 2011 or later and their information is complete. The current recruitment status is unclear.

Study design
This is an observational study that will look at existing data from 12,000 patients. It is a retrospective analysis, meaning it uses information already collected during regular patient care.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoint measures changes in clinical outcome scores from baseline to 8 weeks post-treatment.

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NCT06997549

Retrospective Analyses of the Greenbrook Database Evaluating Mental Health Treatments

Recruiting
Not specifiedAges 5+Observational
Neuronetics
~12,000 participants
Updated 2026-04-09 on ClinicalTrials.gov
What's tested:Patients treated with NeuroStar TMSPatients treated with Esketamine

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
change in clinical outcome scores from baseline to post treatment
Measured over 8 weeks
Depression
OCD
Anxiety Depression
1 sites across 1 states
Pennsylvania1
  • Eleanor Cole, PhD · STUDY_DIRECTOR · Neuronetics

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Eligibility criteria

Inclusion

Male or female reported in database and not an invalid entry
Age reported and not an invalid entry
Treatment date in 2011 or later.
  • change in clinical outcome scores from baseline to post treatment8 weeks

    real-world efficacy of NeuroStar TMS as compared to Esketamine in reducing patients' symptoms, reduction in clinical assessment score like PHQ-9