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Digital Toolkit for Depression in Young Adult Cancer Survivors

This study is testing a digital tool called the AYA Survivors Coping and Emotional Needs Toolkit (ASCENT) to help adolescent and young adult (AYA) cancer survivors manage symptoms of depression after treatment. The ASCENT tool includes daily mood tracking and information about cancer and depression. Researchers want to see which parts of this tool are most helpful in improving depressive symptoms. You might be able to join if you are between 15 and 39 years old, were diagnosed with cancer between ages 12 and 39, and finished your treatment within the last 5 years. The study aims to enroll 208 participants, but its current recruitment status is unclear.

Study design
This is an interventional study with a planned enrollment of 208 participants. It is not specified if it is randomized or blinded.
What's involved
Participants will receive access to the digital ASCENT tool. The primary endpoint measures changes in depressive symptoms from baseline to Week 6.
Compensation
Not stated in the trial record.
Follow-up
Depressive symptoms are measured during the intervention period, from baseline to Week 6.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07173205

Optimizing the AYA Survivors' Coping and Emotional Needs Toolkit

Recruiting
NAAges 15–39InterventionalSupportive care
East Carolina University
~208 participants
Updated 2026-01-07 on ClinicalTrials.gov
What's tested:AYA Survivors Coping and Emotional Needs Toolkit (ASCENT)

At a glance

Recruiting sites
2 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in Depressive Symptoms during Intervention Period
Measured over Baseline to Week 6

Conditions

Depression
Cancer
Adolescent
Young Adult
Adult

Explore related trials

DepressionMalignant Neoplasm

Where it's being run

2 sites across 1 states
North Carolina2

Study leadership

  • Karly M Murphy, PhD · PRINCIPAL_INVESTIGATOR · East Carolina University

Who to contact

AnneMarie Coffey, BS
[email protected]
252-328-6244
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Age at enrollment (adolescents 15-17, emerging adults 18-25, young adults 26-39)
Age at diagnosis (adolescents 12-17, emerging adults 15-25, young adults 15-39)
Time since completion of treatment: 1 month to 5 years
Language: Fluent in English (spoken and written)
Technology: Own smart phone with data plan

Exclusion

Mental Health: Current diagnosis of severe or persistent mental illness
Suicidality: Severe suicidal ideation (including plan and intent)

What this trial measures

  • Change in Depressive Symptoms during Intervention PeriodBaseline to Week 6

    The primary outcome for this study is change in depressive symptoms from Baseline to Week 6. In order to be considered for inclusion in the optimized intervention, intervention components must result in a 3-point decrease in T-score on the Patient-Reported Outcomes Measurement Information System (PROMIS)® Computer Adaptive Test (CAT) for depression between W0 and W6. T-scores have a range from 0 to 100, a mean of 50, and a standard deviation of 10. On this measure, higher scores indicate greater depressive symptoms (worse outcome).