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Self-Help Intervention for Post-9/11 Veterans with Depression or PTSD

This study is looking for post-9/11 Veterans who are experiencing symptoms of depression or post-traumatic stress disorder (PTSD) and functional difficulties. It aims to see if a 6-week self-help program called Resilience Training for Veterans (REST-V) can help improve mental health and daily functioning. REST-V teaches coping strategies and how to find support services. This program will be compared to receiving standard information about resources. The study hopes to enroll 200 Veterans and will track their progress over 40 weeks to see if the self-help program is effective. You can join if you are a Veteran aged 18 or older, served after September 11, 2001, are enrolled at Syracuse or Durham VA, and screen positive for depression or PTSD symptoms and functional impairment.

Study design
This study is comparing a self-help intervention to standard resources for 200 Veterans. It is an interventional study, but the specific phase is not mentioned.
What's involved
Participants will complete 6 brief assessments over 40 weeks. The intervention involves a 6-week self-help program.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for 40 weeks after the start of the study, with assessments at weeks 0, 8, 24, and 40.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07202325

Self-Help Intervention for Post 9/11 Veterans With Depression or PTSD Symptoms

Not Yet Recruiting
NAAges 18+InterventionalTreatment
VA Office of Research and Development
~200 participants
Updated 2026-09-01 on ClinicalTrials.gov
What's tested:Resilience Training for Veterans (REST-V)Usual resources

At a glance

Recruiting sites
0 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Inventory of Psychosocial Functioning (IPF)
Measured over Weeks 0 to 8, 24, and 40

Conditions

Depression
Stress Disorders, Post-Traumatic

Explore related trials

DepressionPost-Traumatic Stress Disorder

Where it's being run

2 sites across 2 states
New York1
North Carolina1

Study leadership

  • Robyn L. Shepardson, PhD · PRINCIPAL_INVESTIGATOR · Syracuse VA Medical Center, Syracuse, NY

Who to contact

Robyn L Shepardson, PhD
[email protected]
(315) 425-4400 · ext. 53519
Email the study team

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Eligibility criteria

Inclusion

Veteran age \>= 18 years who served on or after September 11, 2001
Enrolled at Syracuse or Durham VA Healthcare System (had an encounter in primary care or Military 2VA clinic in past 24 months)
Screen positive for current symptoms of MDD (PHQ-2) or PTSD (PC-PTSD-5)
Report current functional impairment (PHQ-9 item 10)

Exclusion

Inability to communicate in English
Visual impairment that precludes reading self-help materials
Hearing impairment that precludes completing telephone assessments
Cognitive impairment that precludes providing informed consent
Serious mental illness (diagnosis of bipolar disorder or schizophrenia spectrum and other psychotic disorders)
Engaged in psychotherapy/counseling (\>= 2 outpatient therapy visits in past 90 days, scheduled outpatient therapy visit in upcoming 30 days that intends to attend, or psychiatric hospitalization in past 90 days)
Started or had dosage change in psychotropic medication in the past 4 weeks
At imminent risk of suicide or has active high-risk for suicide flag

What this trial measures

  • Inventory of Psychosocial Functioning (IPF)Weeks 0 to 8, 24, and 40

    An 80-item self-report measure of mental-health related psychosocial functional impairment over the past 30 days. The IPF yields domain scores for up to 7 domains (e.g., work, family, self care), with only those domains relevant for the individual being scored, and an overall score. The overall IPF score is an unweighted average of all calculated domain scores, scaled to a range of 0-100. Higher scores indicate greater psychosocial functional impairment (i.e., lower scores = better functioning).