Hyperbaric Oxygen Therapy for Veterans with TBI, PTSD, and Post-Concussive Syndrome

This study is looking at how Hyperbaric Oxygen Therapy (HBOT) might help veterans who have experienced a traumatic brain injury (TBI), post-traumatic stress disorder (PTSD), or post-concussive syndrome. Researchers want to see if HBOT can improve your cognitive function (thinking and memory), mental health (like depression and anxiety), and overall quality of life. You may be able to join if you are a veteran between 18 and 75 years old with a diagnosis of mTBI, PTSD, anxiety, or depression. The study will measure changes in your PTSD symptoms, cognitive abilities, and depression levels before and after HBOT sessions. The study aims to enroll 54 participants, but its current recruitment status is unclear.

Study design
This is an interventional study, meaning participants will receive a specific treatment. It plans to enroll 54 participants.
What's involved
Each Hyperbaric Oxygen Therapy session will last about 95 minutes, including time for descent and 30 minutes of breathing 100% oxygen. Assessments will be done before the first session and immediately after the final session.
Compensation
Not stated in the trial record.
Follow-up
Participants will be assessed immediately after completing the final Hyperbaric Oxygen Therapy session.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07214415

Veterans' Cognitive Function, Mental Health, and Quality of Life After Hyperbaric Oxygen Therapy

Recruiting
PHASE2Ages 18–75InterventionalTreatment
Summit Hyperbarics and Wellness
~54 participants
Updated 2025-10-09 on ClinicalTrials.gov
What's tested:Hyperbaric Oxygen Therapy

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
PTSD Checklist for DSM-5 (PCL-5)
Measured over From baseline assessment prior to first HBOT session to immediately after completion of final HBOT session
+4 more outcomes measured
TBI Traumatic Brain Injury
PTSD - Post Traumatic Stress Disorder
Post Concussive Syndrome
1 sites across 1 states
Idaho1
  • Steven Wyman, MD · PRINCIPAL_INVESTIGATOR · Summit Hyperbarics and Wellness

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  • PTSD Checklist for DSM-5 (PCL-5)From baseline assessment prior to first HBOT session to immediately after completion of final HBOT session

    Self-report questionnaire to assess symptoms of PTSD

  • NeuroTraxFrom baseline assessment prior to first HBOT session to immediately after completion of final HBOT session.

    A computerized cognitive test to measure various cognitive functions, including memory, executive functioning, visual-spatial perception, verbal function, attention, information processing speed, and motor skills.

  • Patient Health Questionnaire-9 (PHQ-9)From baseline assessment prior to first HBOT session to immediately after completion of final HBOT session

    Self-report questionnaire to assess depression severity

  • Generalized Anxiety Disorder 7-item scale (GAD-7)From baseline assessment prior to first HBOT session to immediately after completion of final HBOT session

    Self-report questionnaire to measure anxiety severity

  • World Health Organization Quality of Life (WHOQOL-BREF)From baseline assessment prior to first HBOT session to immediately after completion of final HBOT session

    Self-report questionnaire to rate a person's perception of his/her position in their life in the context of physical, psychological, level of independence, social relationships, environment, and spirituality/religion/personal belief domains and facets