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Breathwork Intervention for Older Adults After Knee Surgery

This study is looking at whether a simple breathwork exercise can help older adults (age 65 and older) who are having knee replacement surgery. We want to see if this type of intervention is practical to use and if people will stick with it. Participants will either watch a 5-minute video guiding them through "Box Breathing" or a 5-minute video of a card game, both delivered online. We'll measure how many people join and stay in the study, and if they provide saliva samples. You can join if you are scheduled for knee replacement surgery within the next week to two months and are in good health.

Study design
This interventional study plans to enroll 32 participants. It is not specified if participants are randomly assigned to groups or if the study is blinded.
What's involved
Participants will engage with either a breathwork video or a card game video for six sessions. The study will last an average of 4.5 months.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed through study completion, which is an average of 4.5 months.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07464860

Feasibility of Breathwork Intervention With Older Adults After Knee Surgery

Recruiting
NAAges 65+InterventionalBasic science
University of Arizona
~32 participants
Updated 2026-07-06 on ClinicalTrials.gov
What's tested:A 5-minute Asynchronous Breathwork InterventionA 5-minute Asynchronous Card Game Video

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Study Feasibility via Recruitment
Measured over Through study completion, an average of 4.5 months
+11 more outcomes measured

Conditions

Surgical Stress Response
Stress Physiological
Stress Physiology
Stress Psychological
Breathing Techniques
Breathing Exercises
Hypothalamic Pituitary Adrenal
Relaxation
Relaxation Therapy
Cortisol
Postoperative Pain
Postoperative Anxiety
Postoperative Depression
Quality of Recovery (QoR-15)

Explore related trials

Total Knee Replacement

Where it's being run

1 sites across 1 states
Arizona1

Study leadership

  • Devon E Cobos Garcia, PhD Candidate · PRINCIPAL_INVESTIGATOR · University of Arizona
  • Ruth E Taylor-Piliae, PhD · STUDY_CHAIR · University of Arizona
  • Thaddeus W W Pace, PhD · STUDY_CHAIR · University of Arizona

Who to contact

Devon E Cobos Garcia, PhD Candidate, MS, BSN
[email protected]
904-477-7960
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

scheduled for elective TKA within the next week to two months (can be second knee, but cannot be a revision of the original knee)
self-reported good health, including denial of debilitating illness that may affect participation in or be potentially exacerbated by deep, controlled breathing (i.e., chronic obstructive pulmonary disorder \[COPD\], symptomatic or advanced heart failure, complete heart block, glaucoma, epilepsy)
denial of conditions that alter cortisol release or that require corticosteroid therapy (i.e., Cushing's syndrome, Addison's disease, pituitary tumors, adrenal gland tumors, asthma)
denial of severe psychiatric or cognitive conditions that warrant the need for a durable power of attorney (DPOA)
able to understand written and verbal English.

Exclusion

currently taking oral, injectable, intranasal, topical, or inhaled corticosteroid medications (i.e., prednisone, hydrocortisone, dexamethasone, methylprednisolone, methylprednisolone acetate, triamcinolone, betamethasone, mometasone, fluticasone, budesonide, clobetasol)
do not have the technology requirements to complete data collection (i.e., participant does not have a smartphone, tablet, laptop, or desktop computer; lack of reliable internet)

What this trial measures

  • Study Feasibility via RecruitmentThrough study completion, an average of 4.5 months

    Enroll a nationwide sample of N=32 older adults (≥65 years of age) scheduled for elective Total Knee Arthroplasty that meet eligibility criteria within the rolling three- to six-month recruitment campaign period

  • Study Feasibility via RetentionThrough study completion, an average of 4.5 months

    Overall study attrition is ≤25%, with no more than 10% differential attrition between the experimental and control groups, calculated by dividing the number of participants who drop out by total participants enrolled in the study.

  • Study Feasibility via Receipt of Saliva SamplesThrough study completion, an average of 4.5 months

    Study team receipt of 80% of salivary cortisol samples collected.

  • Study Feasibility via Postoperative Morbidity Survey CompletionThrough study completion, an average of 4.5 months

    Collection of 80% of postoperative morbidity surveys (Numeric Rating Scale, 11-point; State Anxiety Inventory; Patient-Reported Outcomes Measurement Information System Depression - Short Form 4a; and Quality of Recovery, Short Form)

  • Box Breathing Intervention Feasibility via Box Breathing Completion SurveyThrough study completion, an average of 4.5 months

    80% of the 1-item Box Breathing Completion surveys completed with "Yes", with "Yes" answers indicating the participant completed the Box Breathing session for that day (Postoperative Day 2 and 3) and time (Morning, Afternoon, Evening), and "No" indicating the participant did not complete the Box Breathing session for that day (Postoperative Day 2 and 3) and time (Morning, Afternoon, Evening).

  • Box Breathing Intervention Feasibility via Feasibility of Intervention Measure (FIM)Measured one time on the evening of Postoperative Day 3

    Score ≥15 on the FIM for Box Breathing Intervention per participant. The FIM is a 4-item, Likert-type survey used to measure implementation success. The score range is 4 to 20. The higher the score, the greater the feasibility of implementation.

  • Box Breathing Intervention Acceptability via Acceptability of Intervention Measure (AIM)Measured one time on the evening of Postoperative Day 3

    Score ≥15 on the AIM for Box Breathing Intervention per participant. The AIM is a 4-item, Likert-type survey used to measure implementation success. The score range is 4 to 20. The higher the score, the greater the acceptability of implementation.

  • Box Breathing Intervention Appropriateness via Intervention Appropriateness Measure (IAM)Measured one time on the evening of Postoperative Day 3

    Score ≥15 on the AIM for Box Breathing Intervention per participant. The IAM is a 4-item, Likert-type survey used to measure implementation success. The score range is 4 to 20. The higher the score, the greater the appropriateness of implementation.

  • TriPeaks Video Attention Control Task Feasibility via Attention Control Task Completion SurveyThrough study completion, an average of 4.5 months

    80% of the 1-item Attention Control Task Completion surveys completed with "Yes", with "Yes" answers indicating the participant completed the Attention Control Task (TriPeaks Video) session for that day (Postoperative Day 2 and 3) and time (Morning, Afternoon, Evening), and "No" indicating the participant did not complete the Attention Control Task (TriPeaks Video) session for that day (Postoperative Day 2 and 3) and time (Morning, Afternoon, Evening).

  • TriPeaks Video Attention Control Task Feasibility via Feasibility of Intervention Measure (FIM)Measured one time on the evening of Postoperative Day 3

    Score ≥15 on the FIM for Attention Control Task (TriPeaks Video) per participant. The FIM is a 4-item, Likert-type survey used to measure implementation success. The score range is 4 to 20. The higher the score, the greater the feasibility of implementation.

  • TriPeaks Video Attention Control Task Acceptability via Acceptability of Intervention Measure (AIM)Measured one time on the evening of Postoperative Day 3

    Score ≥15 on the AIM for Attention Control Task (TriPeaks Video) per participant. The AIM is a 4-item, Likert-type survey used to measure implementation success. The score range is 4 to 20. The higher the score, the greater the acceptability of implementation.

  • TriPeaks Video Attention Control Task Appropriateness via Intervention Appropriateness Measure (IAM)Measured one time on the evening of Postoperative Day 3

    Score ≥15 on the IAM for Attention Control Task (TriPeaks Video) per participant. The IAM is a 4-item, Likert-type survey used to measure implementation success. The score range is 4 to 20. The higher the score, the greater the appropriateness of implementation.