Teenthrive 2: Treatments for Improving Mood in Teens

This study, called Teenthrive 2, is looking at ways to improve mood in teenagers with depression. It compares two different approaches: a yoga-based intervention and group cognitive-behavioral therapy (CBT). Both interventions involve twice-weekly sessions, some in-person and some virtual, for 12 weeks. To join, you need to be between 12 and 18 years old and have elevated depressive symptoms, as determined by specific screening scores. The researchers want to see how well these programs are received by participants and if they can meet their goals for recruitment and attendance. This is a pilot study, meaning it's an early step to see if these treatments are practical and acceptable.

Study design
This is a pilot randomized controlled trial (RCT) comparing a yoga-based intervention to group CBT, with 96 participants planned across two sites.
What's involved
Participants will attend twice-weekly sessions (one in-person, one virtual) for 12 weeks and be followed for an additional 3 months. Parents may also be invited to participate in assessments.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for 3 additional months after the 3-month intervention period.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07475845

Teenthrive 2: Treatments for Improving Mood in Teens

Recruiting
NAAges 12–18Interventional
Butler Hospital
~96 participants
Updated 2026-06-10 on ClinicalTrials.gov
What's tested:Yoga-Based Interventiongroup CBT

At a glance

Recruiting sites
2 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Credibility
Measured over Start of treatment
+3 more outcomes measured
Depression in Adolescence

NCT07475845

Where you'd take part

This study runs at 2 sites. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Beth Israel Deaconess Medical Center

    Boston, Massachusettsstudy coordinator listed

    Recruiting

  • Nationwide Children's Hospital

    Columbus, Ohiostudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • Lisa Uebelacker, PhD · PRINCIPAL_INVESTIGATOR · Butler Hospital
  • Shirley Yen, PhD · PRINCIPAL_INVESTIGATOR · Beth Israel Deaconess Medical Center

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  • CredibilityStart of treatment

    Assessed by Credibility scale of Credibility Expectancy Questionnaire

  • ExpectancyStart of treatment

    Assessed by Expectancy scale of Credibility Expectancy Questionnaire

  • Program Satisfaction12 weeks

    Assessed by the Client Satisfaction Questionnaire (CSQ-8)

  • Class AttendanceWeek 0-12

    Assessed via staff observation