Digitally Enhanced Cognitive-Behavioral Therapy for Adolescent Depression and Overweight

This study is looking at a new way to deliver cognitive-behavioral therapy (CBT) to adolescents who have depression and are also overweight or obese. CBT is a type of talk therapy that helps you change unhelpful thinking patterns and behaviors. In this study, participants will receive a six-week, six-session group CBT program delivered online, along with a special digital app. The app is designed to help you practice CBT skills and complete homework between sessions. Researchers want to see if this approach is acceptable and practical for participants, and if the app is also acceptable. To join, you must be 12-17 years old, have a body mass index (BMI) at or above the 85th percentile for your age and sex, and have elevated depression symptoms. You cannot have Type 2 diabetes or certain other medical conditions. The study plans to enroll 60 participants, but its current status is unclear.

Study design
This is an interventional study planning to enroll 60 participants. It is testing a six-week group cognitive-behavioral therapy (CBT) delivered virtually, combined with a digital app.
What's involved
Participants will attend six weekly group CBT sessions online over six weeks. They will also use a digital app to support CBT skills and homework practices.
Compensation
Not stated in the trial record.
Follow-up
Acceptability and feasibility of the intervention and app will be measured at a six-week follow-up after the intervention begins.

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NCT07569991

Digitally Enhanced Cognitive-Behavioral Therapy

Not Yet Recruiting
NAAges 12–17InterventionalPrevention
Colorado State University
~60 participants
Updated 2026-06-05 on ClinicalTrials.gov
What's tested:Cognitive-behavioral therapy (CBT)Digital app

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Intervention Acceptability
Measured over Six-week follow-up
+2 more outcomes measured
Depression in Adolescence
Obesity & Overweight
Cognitive-behavioral Therapy
Mobile Health Technology (mHealth)
Health Behavior
1 sites across 1 states
Colorado1

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Eligibility criteria

Inclusion

Age 12-17 years
Body mass index (BMI) ≥85th percentile for age and sex
Elevated depression symptoms, Center for Epidemiologic Studies-Depression Scale (CES-D) ≥21

Exclusion

Type 2 diabetes; Fasting glucose ≥126 mg/dL or HbA1c ≥6.5
Major developmental (e.g., intellectual developmental disability) or medical or genetic condition (e.g. cancer, Bardet-Biedhl)
Pregnancy/breastfeeding (females)
Bariatric surgery, weight loss medication, or weight loss \>3% in the past 3 months
Active suicidality or self-harm
  • Intervention AcceptabilitySix-week follow-up

    ≥80% of adolescents will report likeability/benefit (≥4 on 1-5 scale where 5=Extremely)

  • Intervention FeasibilitySix-week follow-up

    ≥80% of adolescents will receive 80% group dosage (≥5 of 6 sessions)

  • App AcceptabilitySix-week follow-up

    Of those in CBT+, ≥80% of adolescents will use the app regularly (≥3 times per week)