Down Syndrome clinical trials
47 active trials name this condition. Describe your situation to see which ones you may be eligible for.
By location
- A Study to Assess the Effects of ACI-24.060 in Alzheimer's Disease and in Down Syndrome (ABATE Study)
- A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)
- Metric-Optimized Spectacle Prescriptions for Children With Down Syndrome
- Modulation of the Immune System in Down Syndrome for Improved Outcomes and Neurodevelopment - 1
- Pediatric Down Syndrome Post-Approval Study
- Sleep Intervention and Quality of Life in Down Syndrome
- Endotype DIrected Treatment for OSA in Down Syndrome
- Down Syndrome Obstructive Sleep Apnea
- Evaluating Treatment of ADHD in Children with Down Syndrome
- How Simplified Language Affects Comprehension and Learning in Young Children With Down Syndrome
- Treatment of Obstructive Sleep Apnea With Personalized Surgery in Children With Down Syndrome (TOPS-DS)
- Self-Supporting Nasopharyngeal Airway (ssNPA) Treating Upper Airway Obstruction in Hypotonia
- Treatment of Atopic Dermatitis and Alopecia Areata With Abrocitinib in Individuals With Down Syndrome
- Physical Activity and Community EmPOWERment Project
- Brain Outcomes With Lifestyle Change in Down Syndrome
- Exploring Sympathetic Nervous System Function in Individuals With Down Syndrome
- HomeGrown: A Family-based Lifestyle Intervention to Support Healthy Development of Young Children With Down Syndrome
- Comparison of a Demand Oxygen Delivery
- Measuring Aided Language Development
- Vascular Function in Adults With Down Syndrome
- Collaboration for Down Syndrome Progress (CDP)
- Natural History of Dysregulation and Aging of the Immune System in People With Trisomy 21 With and Without Thymectomy
- Trial-Ready Cohort-Down Syndrome (TRC-DS)
- The Human Trisome Project
- DS-Connect®: The Down Syndrome Registry
- Specimen Collection from Pregnant Women At Increased Risk for Fetal Aneuploidy
- A Study to Learn More About the Health of Persons With Down Syndrome After Treatment for Acute Leukemia
- The ADVANCE (Assay Development and Validation for Pre-Natal and Obstetric Conditions) Study is the Largest U.S.-Based Prospective Study Demonstrating a Circulating Fetal Cell (CFC) Based Approach to Non-invasive Fetal Risk Assessment
- Intensive Multimodal Neurorehabilitation Targeting Neuroplasticity in Pediatric Neurodevelopmental and Chromosomal Disorders
- Families Filming Infants Learning Movement
- Patterns of Neurodevelopmental Disorders
- Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
- Retinal Imaging in Neurodegenerative Disease
- Cholinergic Integrity in Down Syndrome in Association With Aging, Alzheimer's Disease Pathology, and Cognition
- Harness-based Mobility Intervention for Infants With Down Syndrome
- Adapting RDAD for DS
- Drumming Lessons' Influence on Children With Down Syndrome
- A VIRTUAL Three-month Intervention Study of the Effects of a Smartphone Application (HippoCamera) on Memory in Teens and Young Adults With Down Syndrome
- Gamma Frequency Stimulation in Individuals With Down Syndrome
- Escalating Doses of Memantine in Down Syndrome (MEDS-123)
- NAD Augmentation to Prevent or Reverse Alzheimer's Disease in People With Down Syndrome
- Co-Designing and Evaluating Additional Mothers and Babies Program Content for Expectant and New Parents of Children With Down Syndrome
- Computer Models of Airways in Children and Young Adults With Sleep Apnea and Down Syndrome
- Sensitivity of the NIH Toolbox to Stimulant Treatment in Intellectual Disabilities
- Long-term Evaluation of Nasopharyngeal Airway in Hypotonia
- Parent and Infant Inter(X)Action Intervention (PIXI)
- PODER Familiar: Health Promotion for Latino Families of Children With IDD
Guides for people searching for a trial
- Why people get turned down — and what to do nextWhat eligibility criteria are for, what keeps people out, and where to go when the first door closes.
- How your biomarkers decide which trials you qualify forEGFR, HER2, BRAF, PD-L1 and the rest — what they are and why they increasingly gate access.
- How to search for a trial without losing your mindWhere to look, what to gather first, and how to read what you find.
- What Phase 1, 2 and 3 actually mean for youWhat each phase is testing, and how to weigh an early-phase trial against a later one.
- 10 questions to ask before you say yesTreatment, time, cost, safety and your rights. Worth bringing to a screening visit.
- You matched with a trial. What happens now?Phone screens, the screening visit, informed consent, and day one.
Showing active trials that list “Down Syndrome” as a condition. Eligibility shown on each trial is an estimate — the trial's study team makes the final decision.